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Prima-1 结构式

Prima-1

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货号 :BCP26191CAS号 :5608-24-2纯度:98%
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  • 基本信息与产品描述
CAS号 5608-24-2 货号 BCP26191
中文名 Prima-1
英文名 Prima-1
中文别名 2,2-二(羟基甲基)-1-氮杂双环[2,2,2]辛烷-3-酮;
英文别名 2,2-Bis(Hydroxymethyl)-3-Quinuclidinone; 2,2-Dimethylolquinuclidin-3-One;
SMILES O=C1C(CO)(CO)N2CCC1CC2
化学名称
分子式 C9H15NO3 分子量 185.22
纯度 98% 配送 惯例下常温包邮
产品描述 PRIMA-1, named for p53 reactivation and induction of massive apoptosis, is an inhibitor of the growth of cell lines derived from various human tumor types in a mutant p53-dependent manner. PRIMA-1 restores sequence-specific DNA binding and transactivational activity to mutant p53 proteins at relatively high µM to mM concentrations. It is therefore a unique anti-oncogenic substance, working as a re-activator of the apoptotic function of mutant p53 via conformational modulation of function-specific epitopes.
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