即时询价 ×
* 必填项
请填妥以下表格,您将在一分钟内得到邮件机器人给你的报价。
Inquiry Online
×
* Required Fields.
Please complete the form below and we will contact you shortly.
Bulk Inquiry
×
* Required Fields.
Please complete the form below and we will contact you shortly.
CAS号 | 1197996-80-7 | 货号 | BCP29977 |
中文名 | CBL 0137 | ||
英文名 | CBL0137 | ||
中文别名 | |||
英文别名 | CBL-0137; CBL 0137; Curaxin 137; | ||
SMILES | CC(C)NCCN1C2=C(C=C(C=C2)C(=O)C)C3=C1C=CC(=C3)C(=O)C | ||
化学名称 | |||
分子式 | C21H24N2O2 | 分子量 | 336.43 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | CBL0137, also known as Curaxin 137, is a metabolically stable curaxin that activates p53 with an EC50 value of 0.37 µM and inhibits NF-κB with an EC50 of 0.47 µM. CBL0137 inhibits histone chaperone FACT, is efficacious in preclinical orthotopic models of temozolomide-responsive and -resistant glioblastoma. CBL0137 eradicates drug resistant cancer stem cells and potentiates efficacy of gemcitabine in preclinical models of pancreatic cancer. |
相关产品推荐
查看更多 >Tags:CBL0137 供应商,CBL0137 购买,CBL0137 生产,CBL0137 批量,CBL0137 供应,CBL0137 订购,CBL0137 采购