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CAS号 | 552325-73-2 | 货号 | BCP02557 |
关联产品 | A674563HCl(A674563 HCl) | ||
中文名 | A-674563 | ||
英文名 | A-674563 | ||
中文别名 | |||
英文别名 | A 674563;A674563; | ||
SMILES | |||
化学名称 | |||
分子式 | C22H22N4O | 分子量 | 358.44 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | A-674563 is achieved from A-443654 by replacing the indole with a phenyl moiety and getting oral activity. A-674563 slows proliferation of tumor cells with EC50 of 0.4 μM. [1] A-674563 does not inhibit Akt phosphorylation per se, but blocks the phosphorylation of Akt downstream targets in a dose-dependent manner. A-674563 induced Akt blockade results in decreased STS cell downstream target phosphorylation and tumor cell growth inhibiton. A-674563 induces G2 cell cycle arrest and apoptosis in STS cells. |
Tags:A-674563 供应商,A-674563 购买,A-674563 生产,A-674563 批量,A-674563 供应,A-674563 订购,A-674563 采购