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CAS号 | 2682114-54-9 | 货号 | BCP48903 |
中文名 | SP-146 | ||
英文名 | SP-146 | ||
中文别名 | |||
英文别名 | SP 146;SP146; | ||
SMILES | CN1C=C(C=N1)C2=CC3=C(C=C2)C(=NC=N3)NC4=CC(=CC=C4)NC(=O)NC5=CC(=CC=C5)F | ||
化学名称 | |||
分子式 | C25H20FN7O | 分子量 | 453.47 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | SP-96 is a highly potent, selective and non-ATP-competitive Aurora B (IC50=0.316 nM) inhibitor and shows >2000 fold selectivity against FLT3 and KIT. SP-96 shows selective growth inhibition in NCI60 screening, incluing MDA-MD-468 (GI50=107 nM). SP-96 can be used for the research of triple negative breast cancer (TNBC). |
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