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CAS号 | 2170679-45-3 | 货号 | BCP45901 |
中文名 | dBRD9 | ||
英文名 | dBRD9 | ||
中文别名 | |||
英文别名 | |||
SMILES | CN1C=C(C2=C(C1=O)C=NC=C2)C3=CC(=C(C(=C3)OC)CN(C)CC(=O)NCCOCCOCCNC4=CC=CC5=C4C(=O)N(C5=O)C6CCC(=O)NC6=O)OC | ||
化学名称 | |||
分子式 | C40H45N7O10 | 分子量 | 783.84 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | dBRD9 is a potent and selective BRD9 bromodomain degrader composed of the BRD9 inhibitor BI 7273 conjugated to the cereblon E3 ligase ligand pomalidomide. dBRD9 has been used in PROTAC technology and exhibits antiproliferative effects in human AML cell lines. |
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