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CAS号 | 2241237-51-2 | 货号 | BCP48567 |
中文名 | SRX3177 | ||
英文名 | SRX3177 | ||
中文别名 | |||
英文别名 | SRX-3177; SRX 3177; | ||
SMILES | O=C(C1=CC2=CN=C(NC3=CC=C(C4=CSC5=C4OC(N6CCOCC6)=CC5=O)C=C3)N=C2N1C7CCCC7)N(C)C | ||
化学名称 | |||
分子式 | C31H32N6O4S | 分子量 | 584.69 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | SRX3177 is a triple inhibitor of CDK, PI3K, and BRD4, with IC50s of 33 nM (BRD4 BD1), 89 nM (BRD4 BD2), 79 nM (PI3Kα), 83 nM (PI3Kδ), 3.18 μM (PI3Kγ), <2.5 nM (CDK4), 3.3 nM (CDK6), respectively. SRX3177 exerts broad cytotoxic activity against cancer cells, but acts friendly with normal epithelial cells. |
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