即时询价 ×
* 必填项
请填妥以下表格,您将在一分钟内得到邮件机器人给你的报价。
Inquiry Online
×
* Required Fields.
Please complete the form below and we will contact you shortly.
Bulk Inquiry
×
* Required Fields.
Please complete the form below and we will contact you shortly.
CAS号 | 1310726-60-3 | 货号 | BCP19011 |
关联产品 | 1607431-21-9(酒石酸乌帕替尼四水合物) 2050057-56-0(乌帕替尼半水合物) | ||
中文名 | 乌帕替尼 | ||
英文名 | Upadacitinib | ||
中文别名 | |||
英文别名 | ABT494;ABT-494;ABT 494; | ||
SMILES | O=C(N1C[C@@H](CC)[C@@H](C2=CN=C3C=NC(NC=C4)=C4N32)C1)NCC(F)(F)F | ||
化学名称 | |||
分子式 | C17H19F3N6O | 分子量 | 380.1572 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Upadacitinib, also known as ABT-494, is a potent and selective JAK inhibitors in development for rheumatoid arthritis. ABT-494 is approximately 74 fold selective for Jak1 over Jak2 in cellular assays dependent on specific, relevant cytokines. ABT-494 demonstrates efficacy in rat arthritis models. Preliminary evidence suggests that compared to tofacitinib, ABT-494 may spare Jak2 and Jak3 dependent signaling. |
相关产品推荐
查看更多 >Tags:Upadacitinib 供应商,Upadacitinib 购买,Upadacitinib 生产,Upadacitinib 批量,Upadacitinib 供应,Upadacitinib 订购,Upadacitinib 采购