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Ritlecitinib tosylate 结构式

Ritlecitinib tosylate

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货号 :BCP45991CAS号 :2192215-81-7纯度:98%
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  • 基本信息与产品描述
CAS号 2192215-81-7 货号 BCP45991
关联产品 1792180-81-4(Ritlecitinib)
中文名 Ritlecitinib tosylate
英文名 Ritlecitinib tosylate
中文别名
英文别名 PF-06651600; PF 06651600; PF06651600; PF-6651600; PF 6651600; PF6651600;
SMILES CC1CCC(CN1C(=O)C=C)NC2=NC=NC3=C2C=CN3.CC1=CC=C(C=C1)S(=O)(=O)O
化学名称
分子式 C22H27N5O4S 分子量 457.55
纯度 98% 配送 惯例下常温包邮
产品描述 Ritlecitinib, also known as PF-06651600, is a potent and selective JAK3 inhibitor. PF-06651600 is a potent and low clearance compound with demonstrated in vivo efficacy. The favorable efficacy and safety profile of this JAK3-specific inhibitor PF-06651600 led to its evaluation in several human clinical studies. JAK3 was among the first of the JAKs targeted for therapeutic intervention due to the strong validation provided by human SCID patients displaying JAK3 deficiencies.
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