艾乐替尼新

参考资料仅供科学研究，不可用于个人用途。

货号：BCP02589CAS号：1256580-46-7纯度：98%

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CAS号	1256580-46-7	货号	BCP02589
关联产品	1256589-74-8（艾乐替尼盐酸盐）
中文名	艾乐替尼
英文名	Alectinib
中文别名
英文别名	AF 802; AF-802; AF802; CH5424802; CH5424802; CH 5424802; RO5424802; RO 5424802; RO5424802;
SMILES
化学名称
分子式	C30H34N4O2	分子量	482.62
纯度	98%	配送	惯例下常温包邮
产品描述	Alectinib, also known as AF802, or CH5424802 or RO5424802, is a potent, selective, and orally available ALK inhibitor with a unique chemical scaffold, showing preferential antitumor activity against cancers with gene alterations of ALK, such as nonsmall cell lung cancer (NSCLC) cells expressing EML4-ALK fusion and anaplastic large-cell lymphoma (ALCL) cells expressing NPM-ALK fusion in vitro and in vivo. CH5424802 inhibited ALK L1196M, which corresponds to the gatekeeper mutation conferring common resistance to kinase inhibitors, and blocked EML4-ALK L1196M-driven cell growth.

艾乐替尼 新