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Anastrozole 结构式

阿那曲唑

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货号 :BCP02090CAS号 :120511-73-1纯度:98%
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  • 基本信息与产品描述
CAS号 120511-73-1 货号 BCP02090
中文名 阿那曲唑
英文名 Anastrozole
中文别名
英文别名 ZD-1033; ZD 1033; ZD1033; CCRIS 9352; HSDB 7462; ICI D1033; Arimidex;
SMILES CC(C1=CC(CN2N=CN=C2)=CC(C(C)(C)C#N)=C1)(C)C#N
化学名称
分子式 C17H19N5 分子量 293.37
纯度 98% 配送 惯例下常温包邮
产品描述 Anastrozole has high intrinsic potency in vitro and inhibits human placental aromatase with an IC50 of 15 nM. Anastrozole it is 200 times as potent as AG, twice as potent as 4-OHA and one third as potent as fadrozole. [1]. Anastrozole inhibits aromatase by binding competitively to the hem group of the CYP unit of the enzyme thereby reducing estrogen biosynthesis in the periphery and the breast. Anastrozole has little or no effect on other steroid hormones.
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