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Opelconazole 结构式

Opelconazole

参考资料 仅供科学研究,不可用于个人用途。
货号 :BCP36481CAS号 :1931946-73-4纯度:98%
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  • 基本信息与产品描述
CAS号 1931946-73-4 货号 BCP36481
中文名 Opelconazole
英文名 Opelconazole
中文别名
英文别名 PC 945;PC-945;PC945;
SMILES O=C(NC1=CC=C(F)C=C1)C(C=C2)=CC=C2N3CCN(C4=CC=C(OC[C@@H]5CO[C@](C6=CC=C(F)C=C6F)(CN7N=CN=C7)C5)C(C)=C4)CC3
化学名称
分子式 C38H37F3N6O3 分子量 682.73
纯度 98% 配送 惯例下常温包邮
产品描述 PC945 is a novel broad spectrum antifungal agent that potently inhibits Aspergillus fumigatus sterol 14α-demethylase (CYP51A and CYP51B) with IC50 of 0.23 and 0.22 uM, respectively; shows MIC values 0.032 to >8 ug/ml against 96 clinically isolated A. fumigatus strains, demonstrates activity against itraconazole-susceptible and -resistant A. fumigatus growth with IC50 of 0.0012 to 0.034 ug/ml; PC945 is a broad spectrum of pathogenic fungi with MIC 0.0078 to 2 ug/ml, and exhibits activity in vivo.
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