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CAS号 | 2289691-01-4 | 货号 | BCP34062 |
中文名 | MYCi975 | ||
英文名 | MYCi975 | ||
中文别名 | |||
英文别名 | MYCi-975;MYCi 975;NUCC-0200975;NUCC 0200975;NUCC0200975; | ||
SMILES | CN1C(=CC(=N1)C(F)(F)F)C2=C(C(=C(C=C2)OCC3=CC=C(C=C3)Cl)C4=CC(=C(C=C4)Cl)C(F)(F)F)O | ||
化学名称 | |||
分子式 | C25H16Cl2F6N2O2 | 分子量 | 561.30 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | MYCi975 is an orally active MYC inhibitor, which disrupts MYC/MAX interaction, promotes MYC T58 phosphorylation and MYC degradation, and impairs MYC driven gene expression. MYCi975 (NUCC-0200975) exhibits potent anti-tumor efficacy with good tolerability, increases tumor immune cell infiltration, and sensitizes tumors to anti-PD1 immunotherapy. |
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