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10074-G5 结构式

10074-G5

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货号 :BCP09223CAS号 :413611-93-5纯度:98%
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  • 基本信息与产品描述
CAS号 413611-93-5 货号 BCP09223
中文名 10074-G5
英文名 10074-G5
中文别名
英文别名 10074G5;10074 G5;
SMILES
化学名称
分子式 C18H12N4O3 分子量 332.31
纯度 98% 配送 惯例下常温包邮
产品描述 10074-G5 is a c-Myc Max interaction inhibitor. The c-Myc oncoprotein and its partner Max are intrinsically disordered (ID) monomers that undergo coupled folding and binding upon heterodimerization. 10074-G5, similarly to 10058-F4, specifically inhibits this interaction by binding to c-Myc, thus preventing C-Myc specific DNA binding and target genes regulation. 10074-G5 (2.8 microM) is slightly more potent that 10058-F4 (5.2 microM) most likely due to the fact that 10074-G5 binds to a different region of C-Myc than 10054-F4. Thus, the compound may become desirable for probing different interactions.
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