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CAS号 | 413611-93-5 | 货号 | BCP09223 |
中文名 | 10074-G5 | ||
英文名 | 10074-G5 | ||
中文别名 | |||
英文别名 | 10074G5;10074 G5; | ||
SMILES | |||
化学名称 | |||
分子式 | C18H12N4O3 | 分子量 | 332.31 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | 10074-G5 is a c-Myc Max interaction inhibitor. The c-Myc oncoprotein and its partner Max are intrinsically disordered (ID) monomers that undergo coupled folding and binding upon heterodimerization. 10074-G5, similarly to 10058-F4, specifically inhibits this interaction by binding to c-Myc, thus preventing C-Myc specific DNA binding and target genes regulation. 10074-G5 (2.8 microM) is slightly more potent that 10058-F4 (5.2 microM) most likely due to the fact that 10074-G5 binds to a different region of C-Myc than 10054-F4. Thus, the compound may become desirable for probing different interactions. |
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