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Dofetilide 结构式

多非利特

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货号 :BCP04770CAS号 :115256-11-6纯度:99%
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  • 基本信息与产品描述
CAS号 115256-11-6 货号 BCP04770
中文名 多非利特
英文名 Dofetilide
中文别名
英文别名 Tikosyn;UK-68798;UK 68789;UK68789;
SMILES
化学名称
分子式 C19H27N3O5S2 分子量 441.56
纯度 99% 配送 惯例下常温包邮
产品描述 In patients with congestive heart failure and reduced left ventricular function, dofetilide was effective in converting atrial fibrillation, preventing its recurrence, and reducing the risk of hospitalization for worsening heart failure. Dofetilide had no effect on mortality. dofetilide preferentially blocks open (or activated) channels and that the fast inactivation may competitively slow the binding kinetics. Dofetilide acts as a slow-onset/slow-offset open channel blocker of this current at nanomolar concentrations .
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