氨氯地平

参考资料仅供科学研究，不可用于个人用途。

货号：BCP02420CAS号：88150-42-9纯度：98%

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CAS号	88150-42-9	货号	BCP02420
中文名	氨氯地平
英文名	Amlodipine
中文别名
英文别名	Norvasc;Istin;Intervask;
SMILES
化学名称
分子式	C20H25ClN2O5	分子量	408.88
纯度	98%	配送	惯例下常温包邮
产品描述	Amlodipine is a dihydropyridine calcium antagonist (calcium ion antagonist or slow-channel blocker) that inhibits the movement of calcium ions into vascular smooth muscle cells and cardiac muscle cells. Experimental data suggest amlodipine binds to both dihydropyridine and nondihydropyridine binding sites. The contractile processes of cardiac muscle and vascular smooth muscle are dependent upon the movement of extracellular calcium ions into these cells through specific ion channels. Amlodipine inhibits calcium ion influx across cell membranes selectively, with a greater effect on vascular smooth muscle cells than on cardiac muscle cells. Negative inotropic effects, or decreased heart muscle contractility, can be detected in vitro, but such effects have not been seen in intact animals at therapeutic doses. Serum calcium concentration is not affected by amlodipine. Within the physiologic pH range, amlodipine is an ionized compound (pKa = 8.6), and its interaction with the calcium channe