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| CAS号 | 503612-47-3 | 货号 | BCP02451 |
| 中文名 | 阿哌沙班 | ||
| 英文名 | Apixaban | ||
| 中文别名 | |||
| 英文别名 | BMS56224701; BMS 56224701; BMS-56224701; BMS562247-01;BMS 562247-01;BMS-562247-01; | ||
| SMILES | |||
| 化学名称 | |||
| 分子式 | C25H25N5O4 | 分子量 | 459.5 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | Apixaban exhibits a high degree of potency, selectivity, and efficacy on Factor Xa with Ki of 0.08 nM and 0.17 nM for Human Factor Xa and Rabbit Factor Xa, respectively.In vitro, Apixaban prolongs the clotting times of normal human plasma with the concentrations (EC2x) of 3.6 μM, 0.37 μM, 7.4 μM, and 0.4 μM, which are required respectively to double the prothrombin time (PT), modified prothrombin time (mPT), activated partial thromboplastin time (APTT) and HepTest. Besides, Apixaban shows the highest potency in human and rabbit plasma, but less potency in rat and dog plasma in both the PT and APTT assays. | ||
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