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CAS号 | 847591-62-2 | 货号 | BCP02465 |
关联产品 | 1422253-38-0(PRI-724) 780757-88-2(ICG-001) | ||
中文名 | ICG-001 | ||
英文名 | ICG-001 | ||
中文别名 | |||
英文别名 | ICG 001; ICG001;PRI-724;PRI724; PRI 724; ICG001 isomer; ICG-001 isomer; ICG 001 isomer; | ||
SMILES | C1CN(C2CN(C(=O)C(N2C1=O)CC3=CC=C(C=C3)O)CC4=CC=CC5=CC=CC=C54)C(=O)NCC6=CC=CC=C6 | ||
化学名称 | |||
分子式 | C33H32N4O4 | 分子量 | 548.63 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | PRI-724, an isomer or enantiomer of ICG-001, is a potent, specific inhibitor of the canonical Wnt signaling pathway in cancer stem cells with potential antineoplastic activity. Wnt signaling pathway inhibitor PRI-724 specifically inhibits the recruiting of beta-catenin with its coactivator CBP (the binding protein of the cAMP response element-binding protein CREB); together with other transcription factors beta-catenin/CBP binds to WRE (Wnt-responsive element) and activates transcription of a wide range of target genes of Wnt/beta-catenin signaling. Note: ICG-001 and PRR-724 are not the same molecule, which are enantiomer isomers. Many vendors confused them. |
Tags:ICG-001 供应商,ICG-001 购买,ICG-001 生产,ICG-001 批量,ICG-001 供应,ICG-001 订购,ICG-001 采购