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CAS号 | 780750-65-4 | 货号 | BCP48543 |
中文名 | AZD-5672 | ||
英文名 | AZD-5672 | ||
中文别名 | |||
英文别名 | AZD 5672; AZD5672; | ||
SMILES | CCN(C1CCN(CC1)CCC(C2=CC=C(C=C2)S(=O)(=O)C)C3=CC(=CC(=C3)F)F)C(=O)CC4=CC=C(C=C4)S(=O)(=O)C | ||
化学名称 | |||
分子式 | C32H38F2N2O5S2 | 分子量 | 632.78 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | AZD-5672 is an orally active, potent, and selective CCR5 antagonist (IC50=0.32 nM). AZD-5672 shows moderate activity against the hERG ion channel (binding IC50=7.3 μM). AZD5672 is a substrate of human P-gp, and inhibits P-gp-mediated digoxin transport (IC50=32 μM). AZD-5672 can be used for the research of rheumatoid arthritis. |
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