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CAS号 | 1780259-94-0 | 货号 | BCP29859 |
中文名 | ZK756326 dihydrochloride | ||
英文名 | ZK756326 dihydrochloride | ||
中文别名 | |||
英文别名 | ZK 756326 2HCl;ZK-756326 2HCl;ZK756326 2HCl;ZK 756326 dihydrochloride;ZK-756326 dihydrochloride; | ||
SMILES | OCCOCCN1CCN(CC2=CC=CC(OC3=CC=CC=C3)=C2)CC1.[H]Cl.[H]Cl | ||
化学名称 | |||
分子式 | C21H30Cl2N2O3 | 分子量 | 429.38 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | ZK756326 dihydrochloride is a selective, non-peptide CCR8 chemokine receptor agonist (IC50 values are 1.8 and 2.6 μM for human and mouse receptors respectively). Displays no activity at CCR4, CXCR3, CXCR4 and CCR5 and shows > 28-fold selectivity over 26 other GPCRs (less selective at α2A and 5-HT receptors). Induces chemotaxis and inhibits Env-mediated (HIV) cell-cell fusion. |
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