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CAS号 | 714971-09-2 | 货号 | BCP19580 |
中文名 | BMS-599626 | ||
英文名 | BMS-599626 | ||
中文别名 | |||
英文别名 | BMS599626;AC480;BMS 599626;AC-480;AC 480; | ||
SMILES | CC1=C2C(=NC=NN2C=C1NC(=O)OCC3COCCN3)NC4=CC5=C(C=C4)N(N=C5)CC6=CC(=CC=C6)F | ||
化学名称 | |||
分子式 | C27H27FN8O3 | 分子量 | 530.55 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | BMS-599626 is an orally bioavailable inhibitor of the HER1, HER2 and HER4 tyrosine kinases (IC50 =22, 32 and 190 nM, respectively) with potential antineoplastic activity. BMS-599626 inhibits human epidermal growth factor receptors (HER) HER1, HER2 and HER4, thereby inhibiting the proliferation of tumor cells that overexpress these receptors. |
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