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Nelociguat 结构式

Nelociguat

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货号 :BCP16721CAS号 :625115-52-8纯度:98%
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  • 基本信息与产品描述
CAS号 625115-52-8 货号 BCP16721
中文名 Nelociguat
英文名 Nelociguat
中文别名
英文别名 BAY60-4552; BAY 60-4552; BAY-60-4552; BAY604552; BAY-604552; BAY 604552;
SMILES
化学名称
分子式 C19H17FN8O2 分子量 408.39
纯度 98% 配送 惯例下常温包邮
产品描述 Nelociguat, also known as BAY60-4552, is a soluble guanylate cyclase stimulator (sGC stimulator). Soluble guanylate cyclase (sGC) is a key enzyme in the nitric oxide (NO) signalling pathway. On binding of NO to its prosthetic haem group, sGC catalyses the synthesis of the second messenger cyclic guanosine monophosphate (cGMP), which promotes vasodilation and inhibits smooth muscle proliferation, leukocyte recruitment, platelet aggregation and vascular remodelling through a number of downstream mechanisms.
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