Nelociguat
CAS号 | 625115-52-8 | 货号 | BCP16721 |
中文名 | Nelociguat | ||
英文名 | Nelociguat | ||
中文别名 | |||
英文别名 | BAY60-4552; BAY 60-4552; BAY-60-4552; BAY604552; BAY-604552; BAY 604552; | ||
分子式 | C19H17FN8O2 | 分子量 | 408.39 |
生物活性 | Nelociguat, also known as BAY60-4552, is a soluble guanylate cyclase stimulator (sGC stimulator). Soluble guanylate cyclase (sGC) is a key enzyme in the nitric oxide (NO) signalling pathway. On binding of NO to its prosthetic haem group, sGC catalyses the synthesis of the second messenger cyclic guanosine monophosphate (cGMP), which promotes vasodilation and inhibits smooth muscle proliferation, leukocyte recruitment, platelet aggregation and vascular remodelling through a number of downstream mechanisms. | ||
信号通路 | GPCR/G Protein | ||
靶 点 | Guanylate Cyclase |
结构式
本页面部分数据来自于公开的网络资源,所以瀚香生物不能保证其准确性。
不同批次的产品详情请咨询我们的客服:
- 全国免费电话:400-099-8200
瀚香生物(Biochempartner) 的所有产品和服务仅用于科学研究,禁止用于人体和治疗!