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BAY 41-2272 结构式

BAY 41-2272

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货号 :BCP16012CAS号 :256376-24-6纯度:98%
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  • 基本信息与产品描述
CAS号 256376-24-6 货号 BCP16012
中文名 BAY 41-2272
英文名 BAY 41-2272
中文别名
英文别名 BAY-41-2272; BAY41-2272; BAY412272; BAY-412272; BAY 412272;
SMILES C1CC1C2=CN=C(N=C2N)C3=NN(C4=C3C=CC=N4)CC5=CC=CC=C5F
化学名称
分子式 C20H17FN6 分子量 360.39
纯度 98% 配送 惯例下常温包邮
产品描述 BAY 41-2272 is a a soluble guanylate cyclase stimulator (sGC stimulator). BAY 41-2272 inhibits platelet aggregation (IC50 = 36 nM), induces relaxation of phenylephrine-preconstricted rabbit aorta rings (IC50 = 304 nM), and reduces proliferation in smooth muscle.2,3 BAY 41-2272 is effective in vivo. BAY 41-2272 inhibits vascular smooth muscle growth through the cAMP-dependent protein kinase and cGMP-dependent protein kinase pathways. BAY 41-2272 inhibits the development of chronic hypoxic pulmonary hypertension in rats.
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