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WAY-181187 hydrochloride 结构式

WAY-181187 hydrochloride

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货号 :BCP45356CAS号 :554403-08-6纯度:98%
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  • 基本信息与产品描述
CAS号 554403-08-6 货号 BCP45356
中文名 WAY-181187 hydrochloride
英文名 WAY-181187 hydrochloride
中文别名
英文别名 WAY-181187 HCl;WAY181187 HCl;WAY 181187 HCl;
SMILES C1=CC=C2C(=C1)C(=CN2S(=O)(=O)C3=C(N=C4N3C=CS4)Cl)CCN.Cl
化学名称
分子式 C15H14Cl2N4O2S2 分子量 417.32
纯度 98% 配送 惯例下常温包邮
产品描述 WAY-181187 is a potent and selective 5-HT6 receptor agonist. WAY-181187 possesses high affinity binding (2.2 and 4.8 nM, respectively) at the human 5-HT6 receptor and profile as full receptor agonists (WAY-181187: EC50=6.6 nM, Emax=93%). In the rat frontal cortex, acute administration of WAY-181187 (3-30 mg/kg, subcutaneous (s.c.)) significantly increased extracellular GABA concentrations without altering the levels of glutamate or norepinephrine.
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