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NAS-181 methanesulfonate 结构式

NAS-181 methanesulfonate

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货号 :BCP49052CAS号 :205242-62-2纯度:98%
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  • 基本信息与产品描述
CAS号 205242-62-2 货号 BCP49052
中文名 NAS-181 methanesulfonate
英文名 NAS-181 methanesulfonate
中文别名
英文别名 NAS 181 methanesulfonate; NAS181 methanesulfonate;
SMILES CS(=O)(=O)O.CS(=O)(=O)O.C1COC(CN1)COC2=CC=CC3=C2OCC(=C3)CN4CCOCC4
化学名称
分子式 C21H34N2O10S2 分子量 538.63
纯度 98% 配送 惯例下常温包邮
产品描述 NAS-181 methanesulfonate is a 5-HT(1B) receptor antagonist.NAS181 is a potent and selective antagonist of rat 5-HT1B receptor, with a Ki of 47 nM. NAS181 shows 13-fold selectivity for r5-HT1B over bovine 5-HT1B receptor (Ki=630 nM). NAS181 increases the 5-HT turnover and the synaptic concentration of 5-HT by inhibiting terminal r5-HT1B autoreceptors.
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