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CAS号 | 1065110-43-1 | 货号 | BCP45867 |
中文名 | PF-4479745 | ||
英文名 | PF-4479745 | ||
中文别名 | |||
英文别名 | PF-04479745; PF04479745; PF 04479745; PF-4479745; PF4479745; PF 4479745; | ||
SMILES | CC1CNCCC2=C1N=C(N=C2NC)CC3=CC=CC=C3 | ||
化学名称 | |||
分子式 | C17H22N4 | 分子量 | 282.38 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | PF-4479745 is a potent and selective 5-HT2C agonist (EC50 = 10 nM). PF-4479745 displayed robust pharmacology in a preclinical canine model of stress urinary incontinence (SUI) and no measurable functional agonism at the key selectivity targets 5-HT2A and 5-HT2B in relevant tissue-based assay systems. |
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