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CAS号 | 518-34-3 | 货号 | BCP02934 |
中文名 | 汉防己甲素 | ||
英文名 | Tetrandrine | ||
中文别名 | 金艾康;特船君;倒地拱素;粉防己碱; | ||
英文别名 | Hanfangchin A;NSC 77037;Fanchinine;S,S-(+)-Tetrandrine;Sinomenine A;TTD;Tetrandrin;d-Tetrandr; | ||
SMILES | |||
化学名称 | |||
分子式 | C38H42N2O6 | 分子量 | 622.75 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Tetrandrine inhibits voltage-gated Ca2+ currents with an IC50 of 10.1 mM in isolated nerve terminals of the rat neurohypophysis. Tetrandrine is a high-affinity blocker of the type II, maxi-Ca(2+)-activated K+ channel of the rat neurohypophysial terminals with an IC50 of 0.21 mM. Another study shows that Tetrandrine also inhibits Ca(2+)-activated Cl- currents (I(Cl,Ca)) with an IC50 of 5.2 mM. Tetrandrine inhibits the proliferation of human leukemic HL-60 cells via induction of apoptosis. |
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