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CAS号 | 862974-25-2 | 货号 | BCP48201 |
中文名 | N106 | ||
英文名 | N106 | ||
中文别名 | |||
英文别名 | N-106; N 106; | ||
SMILES | COC1=CC=C(C=C1)C2=NN=C(O2)NC3=NC4=C(C=CC=C4S3)OC | ||
化学名称 | |||
分子式 | C17H14N4O3S | 分子量 | 354.38 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | N106 directly activates the SUMO-activating enzyme, E1 ligase, and triggers intrinsic SUMOylation of SERCA2a. Decreased activity and expression of the cardiac sarcoplasmic reticulum calcium ATPase (SERCA2a), a critical pump regulating calcium cycling in cardiomyocyte, are hallmarks of heart failure. |
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