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CAS号 | 40592-88-9 | 货号 | BCP33213 |
中文名 | TLR4-IN-C34 | ||
英文名 | TLR4-IN-C34 | ||
中文别名 | |||
英文别名 | C34;TLR4-C34; | ||
SMILES | CC(C)OC1C(C(C(C(O1)COC(=O)C)OC(=O)C)OC(=O)C)NC(=O)C | ||
化学名称 | |||
分子式 | C17H27NO9 | 分子量 | 389.4 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | TLR4-IN-C34 is a TLR4 inhibitor; attenuates TLR4 signaling in enterocytes and macrophages in vitro, and reduces systemic inflammation in mouse models of endotoxemia and necrotizing enterocolitis (NEC). Also suppresses LPS signaling in human ileum displaying NEC ex-vivo. Displays no significant effects on signaling via TLR2 or TLR9. |
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