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Enpatoran hydrochloride 结构式

Enpatoran hydrochloride

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货号 :BCP48403CAS号 :2101945-93-9纯度:98%
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  • 基本信息与产品描述
CAS号 2101945-93-9 货号 BCP48403
中文名 Enpatoran hydrochloride
英文名 Enpatoran hydrochloride
中文别名
英文别名 M5049 hydrochloride;
SMILES C1C(CN(CC1N)C2=C3C=CC=NC3=C(C=C2)C#N)C(F)(F)F.Cl
化学名称
分子式 C16H16ClF3N4 分子量 356.78
纯度 98% 配送 惯例下常温包邮
产品描述 Enpatoran Hydrochloride is a potent and orally active inhibitor of TLR7/8, with IC50s of 11.1 nM and 24.1 nM in HEK293 cells. Enpatoran Hydrochloride had no activity on TLR3, TLR4 and TLR9. Enpatoran hydrochloride blocks the synthesis of ligands and natural endogenous RNA ligands. Enpatoran Hydrochloride showed good pharmacokinetic properties in vivo. Enpatoran Hydrochloride can be used in the study of congenital and adaptive autoimmune blockade.
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