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CAS号 | 2249801-12-3 | 货号 | BCP32678 |
中文名 | MD2-TLR4-IN-1 | ||
英文名 | MD2-TLR4-IN-1 | ||
中文别名 | |||
英文别名 | |||
SMILES | ClC1=C(C(NC2=CC(C(C3=CC=C(NC=C4)C4=C3)=NN5)=C5C=C2)=O)C(Cl)=CC=C1 | ||
化学名称 | |||
分子式 | C22H14Cl2N4O | 分子量 | 421.28 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | MD2-TLR4-IN-1 is an inhibitor of myeloid differentiation protein 2/toll-like receptor 4 (MD2-TLR4) complex, inhibiting lipopolysaccharides (LPS)-induced expression of tumor necrosis factor alpha (TNF-α) and interleukin-6 (IL-6) in macrophages with IC50 values of 0.89 μM and 0.53 μM, respectively. |
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