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CAS号 | 313674-97-4 | 货号 | BCP39203 |
中文名 | PD-118057 | ||
英文名 | PD-118057 | ||
中文别名 | |||
英文别名 | PD 118057; PD118057; | ||
SMILES | C1=CC=C(C(=C1)C(=O)O)NC2=CC=C(C=C2)CCC3=CC(=C(C=C3)Cl)Cl | ||
化学名称 | |||
分子式 | C21H17Cl2NO2 | 分子量 | 386.27 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | PD 118057 is a human ether-a-go-go (hERG) KV11.1 potassium channel activator, with no major effect on INa, ICa/L, IK1 and IKs currents. PD-118057prevents and reverses QT interval prolongation; Compounds such as PD-118057 may offer new approach in the treatment of delayed repolarization conditions, which occur in inherited or acquired long QT syndrome and congestive heart failure. |
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