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CAS号 | 2758339-04-5 | 货号 | BCP49212 |
中文名 | Tuspetinib hydrate | ||
英文名 | Tuspetinib hydrate | ||
中文别名 | |||
英文别名 | HM43239 monohydrate;HM-43239 monohydrate;HM 43239 monohydrate; | ||
SMILES | |||
化学名称 | |||
分子式 | C29H35ClN6O | 分子量 | 519.1 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Tuspetinib is a selective, reversible type I inhibitor of FMS-like tyrosine kinase 3 (FLT3; CD135; STK1; FLK2) with potential antineoplastic activity. Upon administration, tuspetinib reversibly binds to and inhibits the activity of FLT3. This inhibits the proliferation of FLT3-expressing cancer cells. FLT3, a class III receptor tyrosine kinase (RTK), is overexpressed or mutated in most B-lineage neoplasms and in acute myeloid leukemias. |
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