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CAS号 | 2641993-55-5 | 货号 | BCP48790 |
中文名 | RM-018 | ||
英文名 | RM-018 | ||
中文别名 | |||
英文别名 | RM018;RM 018; | ||
SMILES | CCN1C2=C3C=C(C=C2)C4=CC=CC(=C4)CC(C(=O)N5CCCC(N5)C(=O)OCC(CC3=C1C6=C(N=CC=C6)C(C)OC)(C)C)NC(=O)C(C(C)C)N(C)C(=O)C7CCN(C7)C(=O)C#CCN8CCOCC8 | ||
化学名称 | |||
分子式 | C56H72N8O8 | 分子量 | 985.24 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | RM-018 is a potent, functionally distinct tricomplex KRASG12C active-state inhibitor. RM-018 retains the ability to bind and inhibit KRASG12C/Y96D and could overcome resistance. RM-018 binds specifically to the GTP-bound, active [“RAS(ON)”] state of KRASG12C. |
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