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CAS号 | 2241719-73-1 | 货号 | BCP48490 |
中文名 | ASP2453 | ||
英文名 | ASP2453 | ||
中文别名 | |||
英文别名 | ASP 2453; ASP-2453; | ||
SMILES | CC1=C(C2=C(C=C1)NN=C2)C3=C(C=C4C(=C3OCC(F)(F)F)N=C(N=C4N5CCC6(CC5)CN(C6)C(=O)C=C)OC7CCN(CC7)CCCOC)C8CC8 | ||
化学名称 | |||
分子式 | C40H48F3N7O4 | 分子量 | 747.85 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | ASP2453 is a potent, selective and covalent KRAS G12C inhibitor. ASP2453 inhibits the Son of Sevenless (SOS)-mediated interaction between KRAS G12C and Raf with an IC50 value of 40 nM. |
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