参考资料
在线咨询
购买咨询即时询价 ×
* 必填项
请填妥以下表格,您将在一分钟内得到邮件机器人给你的报价。
Inquiry Online
×
* Required Fields.
Please complete the form below and we will contact you shortly.
Bulk Inquiry
×
* Required Fields.
Please complete the form below and we will contact you shortly.
| CAS号 | 2117405-13-5 | 货号 | BCP33954 |
| 中文名 | SEN177 | ||
| 英文名 | SEN177 | ||
| 中文别名 | |||
| 英文别名 | SEN 177;SEN-177; | ||
| SMILES | CN1C=NN=C1C2CCN(CC2)C3=C(C=CC=N3)C4=CN=C(C=C4)F | ||
| 化学名称 | |||
| 分子式 | C18H19FN6 | 分子量 | 338.38 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | SEN177 is a Glutaminyl cyclase (QPCT) inhibitor. Glutaminyl cyclase modifies N-terminal glutamine or glutamate residues to N-terminal 5-oxoproline or pyroglutamate (named QPCT). QPCT inhibits mutant huntingtin from forming aggregates, but also reduces aggregation of other aggregate-prone proteins containing polyQ or polyA repeats. SEN177 caused dose-dependent decreases in HTT aggregation by a mechanism that requires QPCT inhibition. SEN177 had in vitro activity against polyglutamine toxicity and was able to reduce aggregates in mammalian cells, primary neurons and in a Drosophila model. | ||
在购买和使用瀚香生物产品的过程中，您遇到的任何问题，都可以咨询我们的免费热线：400-099-8200，或者和我们的客服 
。 我们竭诚解决您的一切疑惑，保证您的舒心顺畅。
。 我们竭诚解决您的一切疑惑，保证您的舒心顺畅。相关产品推荐
查看更多 >
Tags:SEN177 供应商,SEN177 购买,SEN177 生产,SEN177 批量,SEN177 供应,SEN177 订购,SEN177 采购