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CAS号 | 145915-58-8 | 货号 | BCP27630 |
中文名 | CGP 52411 | ||
英文名 | CGP 52411 | ||
中文别名 | |||
英文别名 | CGP52411;CGP-52411;DAPH; | ||
SMILES | C1=CC=C(C=C1)NC2=C(C=C3C(=C2)C(=O)NC3=O)NC4=CC=CC=C4 | ||
化学名称 | |||
分子式 | C20H15N3O2 | 分子量 | 329.36 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | CGP 52411, also called DAPH, inhibits and reverses the formation of Aβ42 fibers (β-sheet content of aggregated β-amyloid (1-42): IC50 = 4.5 µM) in neurons associated with Alzheimer's disease. And it is also a selective inhibitor of the epidermal growth factor receptor (EGFR) (IC50 = 0.3 μM in vitro). |
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