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CAS号 | 175026-96-7 | 货号 | BCP16684 |
中文名 | NQDI-1 | ||
英文名 | NQDI-1 | ||
中文别名 | |||
英文别名 | NQDI 1;NQDI1; | ||
SMILES | CCOC(=O)C1=C2C3=CC=CC=C3C(=O)C4=C2C(=CC=C4)NC1=O | ||
化学名称 | |||
分子式 | C19H13NO4 | 分子量 | 319.31 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | NQDI-1 is an inhibitor of ASK1, which attenuates acute ischemic renal injury by modulating oxidative stress and cell death. NQDI-1 was used to study LPS-induced activation and role of ASK1 and p38 in anti-inflammatory cytokine production by macrophages Apoptosis signal-regulating kinase 1 (ASK1) is among the signaling events that lead to postischemic cell death. Inhibition of ASK1 pathway protected hearts from ischemic damage. |
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