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Seocalcitol 结构式

西奥骨化醇

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货号 :BCP38354CAS号 :134404-52-7纯度:98%
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  • 基本信息与产品描述
CAS号 134404-52-7 货号 BCP38354
中文名 西奥骨化醇
英文名 Seocalcitol
中文别名
英文别名 EB-1089;EB 1089;EB1089;
SMILES CCC(CC)(C=CC=CC(C)C1CCC2C1(CCCC2=CC=C3CC(CC(C3=C)O)O)C)O
化学名称
分子式 C30H46O3 分子量 454.68
纯度 98% 配送 惯例下常温包邮
产品描述 Seocalcitol is a vitamin D3 analogue with potential antineoplastic activity. Seocalcitol binds to and activates the vitamin D receptor, a cytoplasmic polypeptide expressed in normal vitamin D responsive tissues, but also overexpressed in certain cancers including hepatocellular carcinoma and pancreatic cancer. Mediated through vitamin D receptor, this agent induces cancer cell differentiation, inhibits cancer cell growth and induces apoptosis. In addition, seocalcitol may also induce growth arrest and apoptosis independent of vitamin D receptor activation through mechanisms that are not fully elucidated.
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