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CAS号 | 163217-09-2 | 货号 | BCP23832 |
中文名 | 伊奈骨化醇 | ||
英文名 | Inecalcitol | ||
中文别名 | 依奈骨化醇; | ||
英文别名 | TX-522; TX 522; TX522; | ||
SMILES | CC(CC#CC(C)(C)O)C1CCC2C1(CCCC2=CC=C3CC(CC(C3)O)O)C | ||
化学名称 | |||
分子式 | C26H40O3 | 分子量 | 400.59 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Inecalcitol is an analog of calcitriol and a vitamin D3 receptor (VDR) agonist, with potential antineoplastic activity. Upon administration, inecalcitol targets and binds to VDR. This activates VDR and VDR-mediated signal transduction pathways. This modulates the VDR-mediated expression of certain genes, including the expression of anti-cancer genes, enhances cellular differentiation, induces tumor cell apoptosis and inhibits tumor cell growth. VDR plays a central role in calcium homeostasis and in the growth of certain cancer cells. |
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