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CAS号 | 1332879-52-3 | 货号 | BCP48928 |
中文名 | Pitstop2 | ||
英文名 | Pitstop2 | ||
中文别名 | |||
英文别名 | Clathrin-IN-1;Pitstop 2; | ||
SMILES | C1=CC=C2C(=C1)C=CC=C2S(=O)(=O)N=C3NC(=O)C(=CC4=CC=C(C=C4)Br)S3 | ||
化学名称 | |||
分子式 | C20H13BrN2O3S2 | 分子量 | 473.36 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Pitstop2 is a selective clathrin-mediated endocytosis (CME) inhibitor. Clathrin-IN-1 selectively inhibits amphiphysin association of clathrin terminal domain (TD) with an IC50 value of 12 μM. Clathrin-IN-1 acutely interferes with receptor-mediated endocytosis, entry of HIV, and synaptic vesicle recycling. |
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