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CAS号 | 1155419-89-8 | 货号 | BCP26024 |
中文名 | BI-224436 | ||
英文名 | BI-224436 | ||
中文别名 | |||
英文别名 | BI 224436; BI224436; | ||
SMILES | CC1=NC2=CC=CC=C2C(=C1C(C(=O)O)OC(C)(C)C)C3=C4C5=C(C=C3)OCCC5=CC=N4 | ||
化学名称 | |||
分子式 | C27H26N2O4 | 分子量 | 442.51 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | BI 224436 is an investigational new drug under development for the treatment of HIV infection. BI 224436 is the first non-catalytic site integrase inhibitor (NCINI). It inhibits HIV replication via binding to a conserved allosteric pocket of the HIV integrase enzyme. This makes the drug distinct in mechanism of action compared to raltegravir and elvitegravir, which bind at the catalytic site. |
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