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Sertraline 结构式

舍曲林

参考资料 仅供科学研究,不可用于个人用途。
货号 :BCP26219CAS号 :79617-96-2纯度:98%
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  • 基本信息与产品描述
CAS号 79617-96-2 货号 BCP26219
中文名 舍曲林
英文名 Sertraline
中文别名
英文别名 Sealdin; Adjuvin; Atruline; CP 51,974-1; Cp-51,974-1; CP 51,974; CP51,974; CP-51,974; Gladem; Tatig; Tresleen; Zoloft;
SMILES
化学名称
分子式 C17H17Cl2N 分子量 306.23
纯度 98% 配送 惯例下常温包邮
产品描述 Sertraline is a selective serotonin uptake inhibitor that is used in the treatment of depression. Sertraline is primarily a serotonin reuptake inhibitor (SRI) with a binding affinity towards the serotonin transporter of Ki=2.8 nM or in that range. Sertraline is also a dopamine reuptake inhibitor, (<50 nmol/L). However, this is not considered a tight binding, and this action is only 10% of its potency as a monoamine reuptake inhibitor. It is a σ1 receptor agonist with 5% of its SRI potency, and an α1-adrenoreceptor antagonist with 1–10% of its SRI potency.
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