曲尼司特

参考资料仅供科学研究，不可用于个人用途。

货号：BCP06359CAS号：53902-12-8纯度：98%

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CAS号	53902-12-8	货号	BCP06359
关联产品	104931-56-8（曲尼司特钠）
中文名	曲尼司特
英文名	Tranilast
中文别名	化学品：2-[[3-(3,4-二甲氧基苯基)-1-氧-2-丙烯基]氨基]苯甲酸;
英文别名	SB252218;SB-252218;SB 252218;
SMILES
化学名称
分子式	C18H17NO5	分子量	327.33
纯度	98%	配送	惯例下常温包邮
产品描述	Tranilast has been approved in Japan and South Korea, since 1982, for the treatment of bronchial asthma, with indications for keloids and hypertrophic scar added in 1993. Tranilast is also used to treat asthma, autoimmune diseases, atopic and fibrotic pathologies, and can also inhibit angiogenesis. The antiproliferative properties of tranilast were found that tranilast elicited an inhibitory effect on fibroblast proliferation in vitro and also suppressed collagen production both in vitro and in vivo . Tranilast also reduced the release of chemical mediators from mast cells and suppressed hypersensitivity reactions. Three-week-old C57Bl/10 and mdx mice received tranilast (~300 mg/kg) in their food for 9 weeks, after which fibrosis was assessed through histological analyses, and functional properties of tibialis anterior muscles were assessed in situ and diaphragm muscle strips in vitro. Tranilast administration did not significantly alter the mass of any muscles in control or mdx mice,