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SAICAR 结构式

SAICAR

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货号 :BCP28964CAS号 :3031-95-6纯度:98%
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  • 基本信息与产品描述
CAS号 3031-95-6 货号 BCP28964
中文名 SAICAR
英文名 SAICAR
中文别名
英文别名 Succino-AICAR; Succinyl-5-aminoimidazole-4-carboxamide-1-ribose-5'-phosphate;
SMILES O=C(O)C[C@@H](C(O)=O)NC(C1=C(N)N([C@H]2[C@@H]([C@@H]([C@@H](COP(O)(O)=O)O2)O)O)C=N1)=O
化学名称
分子式 C13H19N4O12P 分子量 454.28
纯度 98% 配送 惯例下常温包邮
产品描述 SAICAR, also known as Succino-AICAR, is an intermediate in the de novo purine nucleotide synthesis pathway. SAICAR stimulates pyruvate kinase isoform M2 and promotes cancer cell survival in glucose-limited conditions. SAICAR induces protein kinase activity of PKM2 that is necessary for sustained proliferative signaling of cancer cells. SAICAR-mediated PKM2 protein kinase activity is necessary for EGF-induced cancer cell proliferation.
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