即时询价 ×
* 必填项
请填妥以下表格,您将在一分钟内得到邮件机器人给你的报价。
Inquiry Online
×
* Required Fields.
Please complete the form below and we will contact you shortly.
Bulk Inquiry
×
* Required Fields.
Please complete the form below and we will contact you shortly.
CAS号 | 284035-33-2 | 货号 | BCP02421 |
中文名 | NPS 2143 | ||
英文名 | NPS 2143 | ||
中文别名 | |||
英文别名 | NPS-2143;NPS2143;SB-262470;SB 262470;SB262470; | ||
SMILES | |||
化学名称 | |||
分子式 | C24H25ClN2O2 | 分子量 | 408.92 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | NPS 2143 blocks increases in cytoplasmic Ca2+ concentrations with IC50 of 43 nM elicited by activating the Ca2+ receptor in HEK 293 cells expressing the human Ca2+ receptor. NPS 2143 stimulates parathyroid hormone (PTH) secretion from bovine parathyroid cells with EC50 of 41 nM. Moreover, NPS 214 also blocks the inhibitory effects of calcimimetic NPS R-467 on PTH secretion from bovine parathyroid cells and the inhibitory effects of extracellular Ca2+ on isoproterenol-stimulated increases in cyclic AMP formation. In HEK-293 cells transiently expressing hCaSRs, NPS 2143 significantly suppresses the kokumi taste by effectively inhibiting the activity of both GSH (data not shown) and γ-Glu-Val-Gly. A recent study shows that NPS 2143 treatment suppresses low molecular weight fractions of azuki hydrolysate-induced cholecystokinin (CCK) secretion in CaSR-transfected HEK 293 cells. |
Tags:NPS 2143 供应商,NPS 2143 购买,NPS 2143 生产,NPS 2143 批量,NPS 2143 供应,NPS 2143 订购,NPS 2143 采购