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CAS号 | 2376255-48-8 | 货号 | BCP43135 |
中文名 | Ac-FLTD-CMK | ||
英文名 | Ac-FLTD-CMK | ||
中文别名 | |||
英文别名 | |||
SMILES | CC(C)CC(C(=O)NC(C(C)O)C(=O)NC(CC(=O)O)C(=O)CCl)NC(=O)C(CC1=CC=CC=C1)NC(=O)C | ||
化学名称 | |||
分子式 | C26H37ClN4O8 | 分子量 | 569.05 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Ac-FLTD-CMK, a gasdermin D (GSDMD)-derived inhibitor, is a specific inflammatory caspases inhibitor. Ac-FLTD-CMK is effective against caspases-1 (IC50 of 46.7 nM), caspases-4 (IC50 of 1.49 μM), caspases-5 (IC50 of 329 nM), and caspases-11 , but not the apoptotic caspases such as caspase-3. |
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