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CAS号 | 2369979-68-8 | 货号 | BCP40726 |
中文名 | JHU37160 | ||
英文名 | JHU37160 | ||
中文别名 | |||
英文别名 | JHU-37160;JHU 37160; | ||
SMILES | CCN1CCN(CC1)C2=NC3=C(C=CC(=C3)Cl)NC4=C2C=CC=C4F | ||
化学名称 | |||
分子式 | C19H20ClFN4 | 分子量 | 358.8 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | JHU37160 is a Designer Receptors Exclusively Activated by Designer Drug (DREADD) agonist with Ki of 1.9 nM and 3.6 nM for human muscarinic acetylcholine M3 receptors (hM3Dq) and hM4Di in vitro, respectively. And EC50 values are 18.5 nM and 0.2 nM for hM3Dq and hM4Di in fluorescent and BRET-based assays in HEK-293 cells, respectively. |
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