Vebicorvir 新
参考资料
仅供科学研究，不可用于个人用途。
| 规格 | 价格(CNY) | 是否现货 | 购买咨询 |
|---|---|---|---|
| 5.00 mg | ￥1500.00 | In-stock | 购买咨询 |
| 10.00 mg | ￥2800.00 | In-stock | 购买咨询 |
| 25.00 mg | ￥5000.00 | In-stock | 购买咨询 |
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| CAS号 | 2090064-66-5 | 货号 | BCP36939 |
| 中文名 | Vebicorvir | ||
| 英文名 | Vebicorvir | ||
| 中文别名 | |||
| 英文别名 | ABI H0731; ABI-H0731; ABIH0731; ABIH 0731; ABIH-0731; ABI H 0731; ABI H-0731; | ||
| SMILES | C1=CC=C2C(=C1)C(=O)NC3=C(S2(=O)=O)C=CC(=C3)C(=O)NCC4=CN=C(S4)C(F)(F)F | ||
| 化学名称 | |||
| 分子式 | C19H12F3N3O4S2 | 分子量 | 467.44 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | Vebicorvir is a first-generation hepatitis B virus (HBV) core protein inhibitor, has demonstrated effective antiviral activity. ABI-H0731 exhibited selective inhibition of HBV DNA replication (50% effective concentration [EC50] from 173 nM to 307 nM). Most importantly, ABI-H0731 suppressed covalently closed circular DNA (cccDNA) formation in two de novo infection models with EC50s from 1.84 μM to 7.3 μM. Mechanism-of-action studies indicated that ABI-H0731 is a direct-acting antiviral that targets HBV core protein, preventing HBV pregenomic RNA (pgRNA) encapsidation and subsequent DNA replication. | ||
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