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CAS号 | 2064121-65-7 | 货号 | BCP46980 |
中文名 | Asundexian | ||
英文名 | Asundexian | ||
中文别名 | |||
英文别名 | BI1265162; BI-1265162; BI 1265162; BAY2433334; BAY 2433334; BAY-2433334; | ||
SMILES | CCC(C(=O)NC1=CC(=C(C=C1)C(=O)N)F)N2C=C(C(=CC2=O)C3=C(C=CC(=C3)Cl)N4C=C(N=N4)C(F)(F)F)OC | ||
化学名称 | |||
分子式 | C26H21ClF4N6O4 | 分子量 | 592.94 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Asundexian, also known as BAY2433334 and BI1265162, is a blood coagulation factor XIa inhibitor. Asundexian binds directly to the active site of FXIa and thereby inhibits its activity. Asundexian inhibits human FXIa in buffer with an IC50 of 1 nM. BAY 2433334 is a promising development candidate for once-daily oral anticoagulation; it is being evaluated in phase 2 dose-finding studies in patients at risk of thrombosis. |
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